Can you submit an AI-generated image to a scientific journal?

AI-generated image

Can you submit an AI-generated image to a scientific journal?

Not always – and the rules depend heavily on the journal.

In our new Matter of Opinion, “Patchwork policies: Mapping the divergent AI-image rules in scientific journals,” published in Matter by Cell Press, we looked at how journals handle AI-generated visuals.

https://www.cell.com/matter/abstract/S2590-2385(26)00065-2

What we found is a real patchwork of policies.

Some journals completely ban AI-generated images, others allow them only with disclosure, and a few take a more flexible approach. For authors, this creates a confusing landscape when deciding what is acceptable before submission.

🔎 To clarify this landscape, we summarized policies across many major publishers in a table below.

We grouped journals into three categories:
▪️ AI images not allowed.
▪️ Allowed with conditions.
▪️ Flexible or experimental policies.

Summary of selected journal and publisher policies on AI-generated images

Category Publisher / Journal Policy Summary
Flexible / Experimental Wiley Supports AI-assisted concept creation for covers if usage rights are secured and declared.
Royal Society of Chemistry (RSC) AI-assisted graphics are allowed if the tool uses licensed datasets and the output license permits commercial reuse, provided the artwork remains original and suitable for scholarly publication.
BMJ (General Policy) Currently evolving stance; emphasizes transparency and editorial discretion.
Allowed with Conditions ACS Publications Permits AI-generated cover art if tool use is disclosed and authors confirm legal rights for reproduction.
IEEEAllows AI-generated illustrations if tool name, prompt, and disclaimer are cited in the caption.
MDPIAI use in text, figures, or analysis must be declared in Methods or Acknowledgments.
FrontiersAI-generated figures are accepted if accurate, plagiarism-free, and transparently acknowledged.
SAGERequires disclosure of any AI tools used for writing, visualization, or data creation.
Cambridge University PressAI use must adhere to authorship and plagiarism standards and be properly acknowledged.
Lippincott Wolters KluwerAuthors may use AI for figures if disclosed; responsibility for accuracy remains with authors.
MIT PressAllows AI for text or figures if disclosed; prohibits AI in peer review or editorial decisions.
Emerald PublishingPermits AI diagrams and illustrative images if labeled and ethically used, not for data or covers.
BMJAccepts AI-assisted content with full disclosure and editorial review.
World ScientificAI tools can assist with text or visuals if clearly disclosed and reviewed by editors.
ACMAllows AI-generated visuals with complete disclosure of tools and human oversight.
KargerPermits AI use if declared, verified, and cited; hidden AI use breaches ethics.
Medwin Publishers Allows AI images if justified and accompanied by human-written explanatory captions.
Not Allowed PNAS No AI-generated or stock images permitted for covers; artwork must be original and scientifically representative.
Cell Press / ElsevierAI-generated images not accepted for covers or figures, unless AI is part of the research methodology (e.g., biomedical imaging).
Taylor & FrancisProhibits generative AI in the creation or manipulation of figures, images, or research data.
Springer NatureDoes not permit AI-generated images or videos, except for verified scientific data in AI-related research.
Science / AAASAI-generated images or multimedia are not allowed without explicit editorial approval, except for AI/ML studies.
De GruyterDisallows AI-created or modified research images; AI text use must be disclosed.
IOP PublishingAI tools cannot create, alter, or manipulate original data images; only standard charting tools may be used with citation.
PLOSForbids AI use in generating or modifying data images such as blots, microscopy, or gels.
APS (American Physical Society)Prohibits use of fabricated or AI-modified images as substitutes for real data.
Inderscience PublishersDoes not accept figures or images produced with generative AI, any AI text use must be declared.
KeAI PublishingAI-generated images not permitted except with prior editorial approval for cover art or AI-specific research.
IGI GlobalStrictly forbids AI-generated images or videos and any AI manipulation of visual data.
ThiemeAI-generated images are prohibited unless approved by an editor and accompanied by a disclosure statement.
eLifeScreens all submitted figures for manipulation and accepts only authentic, experimentally derived images.
JAMA NetworkDiscourages AI-created medical images unless part of a validated research study; requires full disclosure.
Oxford University Press AI-generated images are banned unless they illustrate AI itself and have editorial consent.

But the differences between policies highlight a deeper issue.

Many journals now ask authors to disclose the AI tool used. However, disclosure alone does not answer a critical question:

Were the images used to train the model created and licensed with permission?

Our conclusion:

Disclosure ≠ Permission.

Simply naming an AI tool does not guarantee that the training data was licensed or that the resulting image can legally be used in a publication.

Beyond legal concerns, AI-generated visuals can also introduce scientific inaccuracies (“hallucinations”) that look convincing but are factually incorrect, and generating them can also have a significant environmental footprint.In our view, AI-generated images should be allowed only when the models were trained on datasets developed or licensed with proper permissions. At the same time, there is a need for a clearer, unified approach that encourages innovation without compromising scientific integrity.

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